Heme oxygenase-1 (HO-1) is an inducible stress protein that catalyzes the oxidative conversion of heme to carbon monoxide (CO), iron, and biliverdin (BV), the latter of which is converted to bilirubin (BR) by biliverdin reductase.HO-1 has been implicated as a cytoprotectant in various models of acute organ injury and disease (i.e., lung, kidney, he
To avoid disrepair and over-repair and improve gas turbine reliability and availability, gas-path diagnosis is an effective technical means of disseminating early warning information for evolving or impending deterioration.Aiming at the problems of existing gas-path diagnosis methods (i.e., data-driven based gas-path diagnosis and a model-based gas
The myosin light chains (MLCs) of non-muscle myosin II are known to regulate cellular architecture and generate cellular forces; they also have an increasingly emerging role in the progression of cancer.The phosphorylation state of the myosin light chains controls the activity of myosins that are implicated in invasion and proliferation.In cancers,
BK virus (BKV) associated nephropathy affects 1-10% of kidney transplant recipients, leading to graft failure in about 50% of cases.Immune responses cbd against different BKV antigens have been shown to have a prognostic value for disease development.Data currently suggest that the structural antigens and regulatory antigens of BKV might each trigg